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Question

In a bacterial cell, in the absence of ligase enzyme

A
The accumulation of Okazaki fragments occurs
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B
The RNA primer is not synthesized
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C
The replication is not at all initiated
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D
The replication becomes continuous
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Solution

The correct option is A The accumulation of Okazaki fragments occurs
In a bacterial cell, in the absence of ligase enzyme accumulation of Okazaki fragments occurs. DNA ligase is a specific type of enzyme that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond. DNA ligase has applications in both DNA repair and DNA replication. Okazaki fragments are short, newly synthesized DNA fragments that are formed on the lagging template strand during DNA replication. Enzyme ligase connects (ligates) the two Okazaki fragments into one continuous newly synthesized complementary strand.
Thus, the correct answer is option A.

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