Question

In a blood sample, a WBC has a nucleus with drum-sticks. This indicates that the blood sample has come from a person who is

• A. Heamphilic
• B. Diabatic
• C. Female
• D. Sickle cell-anemic

Answer 1

Answer: (C)

Female

Neutrophils are sexually dimorphic. Neutrophils from females exhibit a small additional X chromosome structure, known as a "neutrophil drumstick".

Drumsticks are differentiated from other nuclear appendages that may occasionally be seen in both sexes.

Drumsticks usually appear when two XX chromosomes are present. The active X chromosome is randomly distributed within nuclear lobes, but the inactive X preferentially appears in drumsticks. Typical drumsticks are rarely seen in normal men.

So the answer is 'Female'.