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Question

In a chromosome there is a specific DNA sequence which is responsible for initiating replication is

A
rop
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B
Palindromic nucleotide sequence
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C
Promoter
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D
Ori
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Solution

The correct option is D Ori
Replication
Replication is the process by which a double stranded DNA molecule forms the identical daughter DNA molecules.

Palindromic nucleotide sequence
Recognition sequence is the site where the DNA is cut by a restriction endonuclease. They are palindromic sequences.

Palindromic sequences are nucleotide sequences that read the same on the two strands when orientation of the reading is kept the same, that is, 5'→3'direction. For example, GAATTC from 5’ to 3’ on one DNA strand and CTTAAG from 3’ to 5’ in the complementary DNA strand is a palindromic sequence.

Ori
The ori site or origin of the replication site is a specific nucleotide sequence on the vector DNA that initiates replication. Any piece of DNA when linked to this sequence can be made to replicate within the host cells.

Promoter
Promoter is a specific sequence of nucleotides on DNA that indicates the initiation point for RNA polymerase to start transcription of DNA to create RNA.

Rop
Rop is a nucleotide sequence in the pBR322 cloning vector that codes for the proteins involved in the replication of the plasmid.

Final answer
(B) Ori

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