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Question

In a typical DNA molecule, the proportion of thymine is 20% of the N bases. Find out the percentages of other N bases.

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Solution

According to the rule given by Chargaff, A + G = C + T.
Adenine (A) will always pair with Thymine (T). This means that A = T.
Cytosine (C) will always pair with Guanine (G). This means that C = G.
Since the proportion of thymine T = 20%, so, A = 20%.
G + C = 100 - 40% = 60%
So, G = 30% and C = 30%.
Therefore, the answer is T = 20%, A = 20%, G = 30% and C = 30%.

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