In animal cell, taxol (an anticancer drug) disrupts microtubule formation by binding to microtubules and accelerating their assembly from the protein precursor, tubulin. Thus, stopping mitosis. Taxol must affect _________.

The fibres of the mitotic spindle

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Anaphase

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Formation of centrioles

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The S phase of the cell cycle

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Solution

The correct option is D The fibres of the mitotic spindle
A. The fibers of the mitotic spindle
Reason : Taxol (generic name paclitaxel) is one of the most important anticancer drugs available in the world. It is related with the destruction of microtubules. Due to this, the formation of mitotic spindle fiber formation get arrested and as a result, the cell division come to a hold.
So the correct option is A.

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Similar questions

List I	List II
(A) $G_{2}$ phase	(I) Fusion of microtubules to form spindle apparatus
(B) Prometaphase	(II) Production of energy required for spindle formation
(C) Anaphase	(III) Recombination of genetic material
(D) Pachytene	(IV) Contraction of tubulin proteins
	(V) Reappearance of plasmosome

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