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Question
In diseases that show X-linked inheritance, the females are usually the ______.
In diseases that show X-linked inheritance, the females are usually the ______.
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Solution
The correct option is B Carriers
In females, having a defective allele on the X-chromosome do not express the disorder, when the allele is recessive and the normal allele masks the activity of this allele. Males however having a single X chromosome, invariably expresses the disease, if they possess the defective allele. Since males get their X chromosome from the mother, the disease pedigree is from the carrier mother to her son.
Carriers
In females, having a defective allele on the X-chromosome do not express the disorder, when the allele is recessive and the normal allele masks the activity of this allele. Males however having a single X chromosome, invariably expresses the disease, if they possess the defective allele. Since males get their X chromosome from the mother, the disease pedigree is from the carrier mother to her son.
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