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Question

In Griffith's experiments, mice died when injected with

A
Heat killed S-strain
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B
Heat killed S-strain combined with R-strain
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C
Heat killed R-strain
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D
Live R-strain
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Solution

The correct option is B Heat killed S-strain combined with R-strain
In the experiment by Griffith, S-strain is the smooth and virulent form of Streptococcus pneumoniae. R strain is rough and harmless.
1. The immune system of the mouse recognizes the rough strain of bacteria and the mouse lives.
2. The mouse dies as it cannot recognize the smooth strain.
3. When the S strain is killed by heat and injected the mouse survives.
4. But when live R strain and heat-killed S strain are mixed and injected the mouse dies.
This experiment proves the transformation of DNA in bacteria.
Thus the correct answer is option B.

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