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Griffith's Experiment

In Griffith’s...

Question

In Griffith’s transformation experiment, the conversion of R strain to S strain was due to:

A

Transfer of transforming principle from live R strain to heat-killed S strain bacteria

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B

Uptake of naked DNA from medium by heat-killed S strains

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C

Transfer of transforming principle from heat-killed S strains to live R strains

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D

Uptake of transforming principle from medium by heat-killed S strains to become live S strains.

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Solution

The correct option is C
Transfer of transforming principle from heat-killed S strains to live R strains

The transforming principle, later identified as DNA, passed on from the heat-killed S strains, enabled the R strains to synthesise a smooth polysaccharide capsule and become virulent.

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Similar questions

Q. In Griffith’s transformation experiment, the conversion of R strain to S strain was due to:

Q. To describe transforming principle, Frederick Griffith performed series of experiments by selecting two strains of Streptococcus pneumoniae namely S-strain (virulent) and R-strain (non-virulent).
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Q. Assertion :In Griffiths experiment, a mixture of heat-killed virulent bacteria R and live non-virulent bacteria 5, lead to the death of mice. Reason: Transforming principle got transferred from heat-killed R strain to S strain and made it virulent.

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Q. In a series of experiments with Streptococcus and mice F. Griffith concluded that R-strain bacteria had been transformed. Explain.

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