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Question

In higher vertebrates, the immune system can distinguish self-cells and non-self cells. If this property is lost due to genetic abnormality and it attacks self-cells, then it leads to

A
Active immunity
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B
Graft rejection
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C
Auto-immune disease
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D
Allergic response
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Solution

The correct option is C Auto-immune disease
Autoimmunity :
The condition of the body in which the body fails to differentiate between self and non-self cells and start attacking self cells is called autoimmunity.
Examples include rheumatoid arthritis.




Active immunity :
When a host is exposed to antigens (maybe in the form of living or dead microbes or other proteins), antibodies are produced in the host body. This type of immunity is called active immunity. Active immunity is slow and maybe natural and artificial.



Allergy :
Allergy is the exaggerated response of the immune system of the body to certain antigens. It is basically hypersensitivity of the body. The type of antibody produced during allergy is IgE.




Graft rejection :
During the transplant of a part of the body, if the recipient's immune system recognizes the donor tissue as non-self and triggers an immune response which results in the rejection of the graft, it is called graft rejection.

Final answer :
(a) Auto-immune disease


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