Question

In normal healthy individual percentage of adult and foetal haemoglobin, HbA$:$ HbA$2:$ HbF is?

• A. $96:2:2$
• B. $50:45:5$
• C. $45:45:10$
• D. $80:10:10$

Answer 1

The correct option is A $96:2:2$

The HBA2 gene provides instructions for making a protein called alpha-globin. This protein is also produced from a nearly identical gene called HBA1. These two alpha-globin genes are located close together in a region of chromosome 16 known as the alpha-globin locus. A fetal hemoglobin test (Hgb electrophoresis) measures the level of fetal hemoglobin (Hemoglobin F or HbF) in the blood of infants and children. At puberty, all HbA and HbA2 will replace HbF from the body .

So, the correct answer is '96:2:2'.