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Question

In prokaryotes, the predominant site (or primary step) of control of gene expression is at

A

Control of rate of transcriptional initiation
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B

Control of rate of initiation of replication
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C

Processing level
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D

Control of rate of translational initiation
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Solution

The correct option is A
Control of rate of transcriptional initiation
Regulation of gene expression in prokaryotes
Transcription is the process of formation of RNA from DNA. Controlling the rate of transcription initiation is the predominant mechanism of controlling gene expression in prokaryotes. The interaction of RNA polymerase with a given promoter is influenced by certain accessory proteins. These regulate the ability of RNA polymerase to recognise the start sites. The regulatory proteins indirectly or directly influencing the activities of RNA polymerase include inducers and repressors.

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