Question

In regard to bone cell development, which of the following sequences is correct ?

• A. osteoblasts → osteoclasts → osteocytes
• B. osteogenic cells → osteoclasts → osteocytes
• C. osteogenic cells → osteocytes → osteoclasts
• D. osteogenic cells → osteoblasts → osteocytes

Answer 1

The correct option is D osteogenic cells → osteoblasts → osteocytes

Osteoblasts are the cells that form new bone. They also come from the bone marrow and are related to structural cells. They have only one nucleus. Osteoblasts work in teams to build bone. They produce new bone called "osteoid" which is made of bone collagen and other protein. Then they control calcium and mineral deposition. They are found on the surface of the new bone. Osteocytes are cells inside the bone. They also come from osteoblasts. Some of the osteoblasts turn into osteocytes while the new bone is being formed, and the osteocytes then get surrounded by new bone. They are not isolated, however, because they send out long branches that connect to the other osteocytes. These cells can sense pressures or cracks in the bone and help to direct where osteoclasts will dissolve the bone.