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Question

In RNAi, genes are silenced using

A
ssDNA
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B
dsDNA
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C
dsRNA
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D
ssRNA
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Solution

The correct option is C dsRNA
RNAi takes place in all eukaryotic organisms as a method of cellular defense. This method involves silencing of a specific mRNA due to a complementary dsRNA molecule that binds to and prevents translation of the mRNA (silencing). The source of this complementary RNA could be from an infection by viruses having RNA genomes or mobile genetic elements (transposons) that replicate via an RNA intermediate.
So, the correct answer is 'dsRNA'.

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