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Question
In some autoimmune diseases, capillaries may become damaged resulting in high levels of albumin, proteins and blood cells appearing in the urine. Which region of the nephron contains capillaries that, when damaged, could cause this appearance in urine?
In some autoimmune diseases, capillaries may become damaged resulting in high levels of albumin, proteins and blood cells appearing in the urine. Which region of the nephron contains capillaries that, when damaged, could cause this appearance in urine?
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Solution
The correct option is A Renal corpuscle
The glomerulus and its surrounding Bowman's capsule constitute a renal corpuscle, the basic filtration unit of the kidney. There is a negative charge fixed on each of these layers. This negative charge repels plasma components, which also have a negative charge. Size does matter however, and smaller solutes can overcome this charge barrier and pass through the gaps in the filtration barrier. Larger solutes however, like plasma proteins, with a net negative charge are repelled. So if Renal Corpuscles are damaged, then high levels of albumin, proteins and blood cells appear in the urine.
The glomerulus and its surrounding Bowman's capsule constitute a renal corpuscle, the basic filtration unit of the kidney. There is a negative charge fixed on each of these layers. This negative charge repels plasma components, which also have a negative charge. Size does matter however, and smaller solutes can overcome this charge barrier and pass through the gaps in the filtration barrier. Larger solutes however, like plasma proteins, with a net negative charge are repelled. So if Renal Corpuscles are damaged, then high levels of albumin, proteins and blood cells appear in the urine.
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