Question

In vitro repeated replication of selected DNA components is

• A. Gene amplification
• B. Gene replication
• C. Gene synthesis
• D. Pleiotropy

Answer 1

The correct option is A Gene amplification

Gene amplification can occur in situ, forming a so-called homogeneously staining region (HSR) in the normal chromosomal location of the gene (many copies of the gene are present as tandem repeats) or as so-called double minute chromosomes (extra chromosomal fragments of DNA containing multiple copies of the amplified gene). Gene amplification can also occur as an artifact when tumor cells are cultured in vitro.

So, the correct answer is 'Gene amplification.'