Numerous viruses infect plant, however, none of them so far is known as pathogen to animal and human beings. Only three families, Bunyaviridae, Rhabdoviridae and Reoviridae contain viruses known to infect plant, animal and human. Philippe Colson and coworkers from France reported in the recent issue of PLoS ONE that Pepper mild mottle virus (PMMoV), a plant virus might infecting human being .