Jay has been diagnosed with a mitochondrial disease. His wife does not have the disease and currently is pregnant. What is the risk that this child will have the disease?

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Solution

The correct option is A 0%
Mitochondrial diseases are maternally inherited. This is because the sperm does not contribute cytoplasm to the zygote. Only the sperm nucleus enters the ovum during fertilization.

So, Jay cannot pass on the disease to his child. Since his wife is normal, the child will not have the disease.

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