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Question

Ketoglutarate dehydrogenase brings about

A
Oxidation and decarboxylation
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B
Oxidation
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C
Decarboxylation
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D
Reduction
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Solution

The correct option is B Oxidation and decarboxylation
Ketoglutarate dehydrogenase is an essential enzyme that converts α ketoglutaric acid to succinyl CoA in Krebs' cycle. Such a conversion oxidises the ketoglutaric acid of hydrogen and also removes one CO2. Hence it is a oxidation and decarboxylation reaction. So the answer is 'Oxidation and decarboxylation'.

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