Krebs' cycle starts with the formation of six carbon compound by reaction between

fumaric acid and pyruvic acid

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OAA and acetyl CoA

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malic acid and acetyl CoA

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succinic acid and pyruvic acid

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Solution

The correct option is C OAA and acetyl CoA
Acetyl CoA (2-carbon compound) combines with oxaloacetate (4-carbon compound) in the presence of condensing enzyme citrate synthase to form a tricarboxylic 6-carbon compound called citric acid. It is the first product of kerbs' cycle. CoA is liberated.
$A c e t y l C o A + O x a l o a c e t i c a c i d + H_{2} O C i t r a t e s y n t h a s e - ------------- \to C i t r a t e + C o A$

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