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Question

Kreb’s cycle was discovered by Krebs in pigeon muscles in 1940. Which step is called gateway step/link reaction/transition reaction in respiration?

A
Glycolysis
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B
Formation of acetyl-coA
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C
Citric acid formation
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D
ETS terminal oxidation
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Solution

The correct option is B Formation of acetyl-coA
Acetyl CoA formation is vital in the process of respiration. Pyruvic acid is the end product of glycolysis. It is then transformed into acetyl CoA. Acetyl CoA functions as substrate for Krebs cycle. Acetyl CoA is the entry point into Krebs cycle. Hence, Formation of acetyl-coA is called gateway step/link reaction/transition reaction in respiration.

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