Look at the following complementary sequences of a single DNA molecule, and identify the correct mRNA sequence that gets transcribed from it:
5’ TAGGCGCATT 3’
3’ ATCCGCGTAA 5’
5’ UAGGCGCAUU 3’
Of the two parental DNA strands, the one that runs along the 5’→ 3’ direction is the sense strand or the coding strand, while the one that runs in the 3’→ 5’ direction is the antisense strand or template strand. The antisense strand serves as template for the new mRNA strand. Moreover, RNA polymerase can add nucleotides only in the 5’→ 3’ direction and hence, the newly forming mRNA strand would be aligned 5’→ 3’. The newly transcribed mRNA strand thus, has a sequence that is complementary to the template strand and similar to the coding strand, with the difference that ‘U’ replaces ‘T’.