Major complication/s associated with prolonged glucocorticoidtherapy is/are
A
Gastrointestinal ulcers
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B
Ostroporosis
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C
Increased secretion of HCI in stomach and pepsinogen
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D
All of these
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Solution
The correct option is D All of these
Glucocorticoids are steroids that reduce inflammation throughout the body. The complications involved in prolonged glucocorticoid therapy includes immunosuppression, delay in wound healing. It raise the blood sugar which can trigger temporary and possibly permanent diabetes mellitus, Calcium absorption may be suppressed and osteoporosis may result. ulcers and gastritis are more likely. Also, there is an increased secretion of HCl in the stomach.