Question

Match the column I with column II and select the correct option.

	Column I		Column II
A	ANF	1	Regulates blood calcium levels
B	MSH	2	Decreases blood pressure
C	GIP	3	Pigmentation
D	TCT	4	Inhibits gastric secretion

• A. A- 4, B- 1, C- 2, D- 3
• B. A- 2, B- 1, C- 4, D- 3
• C. A- 4, B- 1, C- 3, D- 2
• D. A- 3, B- 2, C- 4, D- 1
• E. A- 2, B- 3, C- 4, D- 1

Answer 1

The correct option is E A- 2, B- 3, C- 4, D- 1

• Atrial natriuretic peptide (ANP) or atrial natriuretic factor (ANF) is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. ANF acts to reduce the water, sodium and adipose loads on the circulatory system, thereby reducing blood pressure.
  
• The melanocyte-stimulating hormones ( MSH) are peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland. They stimulate the production and release of melanin (melanogenesis) by melanocytes in skin and hair. An increase in MSH will cause skin darkening in humans.
  
• GIP is a peptide hormone, secreted by the stomach, which stimulates intestinal secretions and insulin release as part of the digestive process; GIP inhibits the secretion of gastric acids and of pepsin.
  
• Calcitonin is a hormone, that is produced in humans by the parafollicular cells (commonly known as C-cells) of the thyroid gland. Thyrocalcitonin (TCT) helps to regulate levels of calcium and phosphate in the blood, opposing the action of parathyroid hormone. This means that it acts to reduce calcium levels in the blood.
  Hence , option E is correct.