Question

Match the items in Column - I with Column - II and choose the correct alternative -

Column - I	Column - II
A. Sickle-cell anaemia	1. $7^{th}$ chromosome
B. Phenylketonuria	2. $4^{th}$ chromosome
C. Cystic fibrosis	3. ${11}^{th}$ chromosome
D. Huntington's disease	4. X-chromosome
E. Colour blindness	5. ${12}^{th}$ chromosome

• A. A-1, B-3, C-4, D-2, E-5
• B. A-2, B-3, C-4, D-5, E-1
• C. A-2,,B-1, C-3, D-5, E-4
• D. A-4, B-5, C-3, D-2, E-1
• E. A-3, B-5, C-1, D-2, E-4

Answer 1

The correct option is E A-3, B-5, C-1, D-2, E-4

• Sickle cell anaemia is a recessive autosomal disease and its gene is located on chromosome number 11.
• Phenylketonuria is an autosomal recessive disease, a gene located on chromosome number 12.
• Cystic fibrosis occurs due to mutation of gene present on chromosome number 7.
• Huntington's disease mainly occurs due to mutation in a gene present on chromosome number 4.
• Color blindness is a sex-linked recessive disorder that is located on the X chromosome.

Thus the correct answer is option E.