Question

Mention one role of the sigma factor in transcription.

Answer 1

Role of sigma factor in transcription:-

1. In order for transcription to begin in bacteria, a protein called a sigma factor (also known as a specificity factor) is required.
2. It is a bacterial transcription initiation factor that permits RNA polymerase (RNAP) to specifically bind to gene promoters.
3. The RNA polymerase core enzyme's promoter specificity is influenced by the binding of sigma factors, which then directs the selective transcription of multiple gene sets and coordinates gene expression in response to numerous environmental and endogenous stimuli.