Question

mRNAs are capped by

• A. Modified GTP at the 3’ end and modified ATP at the 5’ end
• B. Modified Poly G tail at the 3’ end and ATP at the 5’ end
• C. Modified GTP at the 5’ end and Poly A tail at the 3’ end
• D. Modified GTP at the 3’ end and Poly A tail at the 5’ end

Answer 1

The correct option is C Modified GTP at the 5’ end and Poly A tail at the 3’ end

The newly transcribed mRNA strand undergoes processing before it proceeds into the cytoplasm. This processing involves capping, which is the addition of a modified form of guanosine triphosphate (GTP) at the 5’ end, and tailing, which involves the addition of about 200-250 adenines at the 3’ end to form the poly A tail.