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Question

Myelogenous leukemia is due to

A
Complete loss of one chromosome of 21st chromosome pair
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B
Translocation of a part of chromosome number 8 in to chromosome 14
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C
Deletion in long arm of chromosome 18
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D
Deletion of log arm of chromosome 22 and its addition to chromosome 9
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Solution

The correct option is D Deletion of log arm of chromosome 22 and its addition to chromosome 9
  • Myelogenous leukemia is a disease in which the bone marrow makes too many white blood cells.
  • Chronic myelogenous leukemia (also called CML or chronic granulocytic leukemia) is a slowly progressing blood and bone marrow disease that usually occurs during or after middle age and rarely occurs in children.
  • It is due to the Deletion of the long arm of chromosome 22 and its addition to chromosome 9'.
  • So, the correct answer is 'Deletion of the long arm of chromosome 22 and its addition to chromosome 9'.

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