It is characterized by swelling and thickening of the skin, especially in the lower part of the legs.
It occurs due to the insufficiency of thyroid hormones in the body.
Thyroid hormone:
The thyroid hormones are secreted by the thyroid gland, which is located in front of the neck.
These hormones are important in the regulation of many functions and aspects of the human body, such as temperature regulation, energy levels, weight, hair, nail growth, and more.