T-lymphocytes | B-lymphocytes |
Produced in the bone marrow and migrate to the thymus gland for final maturation. | Produced in the bone marrow and mature in the bone marrow itself. |
If the antigen comes from outside the body, it needs to be presented to the T-cells on the surface of an antigen presenting cell. | Recognize and bind antigen particles without having to be presented by an antigen presenting cell. |
Cell- mediated immunity | Antibody mediated (humoral) immunity |