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Question

One acetyl coA molecule entering the TCA cycle gives rise to molecules of NADH.

A
two
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B
three
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C
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D
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Solution

The correct option is B three
There are 3 points during the Kreb's cycle, when NAD is reduced to NADH.
1. Oxidative deecarboxylation of isocitrate to α-ketoglutaric acid, catalysed by isocitrate dehydrogenase.
2. Oxidative decarboxylation of α-ketoglutaric acid to succinyl Co-A, catalysed by α-ketoglutarate dehydrogenase.
3. Dehydrogenation of malate to oxaloacetate, catalysed by the enzyme malate dehydrogenase.

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