One gene-one enzyme hypothesis was postulated by

R. Franklin

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Hershey and Chase

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A. Garrod

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Beadle and Tatum

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Solution

The correct option is D Beadle and Tatum
Beadle and Tatum did classical experiments on Neurospora crassa to prove that in a multistep biochemical pathway, each step is controlled by different enzymes and each of these enzymes are encoded by specific gene. This is called as one gene one enzyme hypothesis
So, the correct answer is 'Beadle and Tatum'

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