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Question

Oxidation of pyruvate to acetyl coA is catalysed by the enzyme pyruvate .

A
dehydrogenase
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B
catalase
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C
phosphorylase
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D
esterase
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Solution

The correct option is A dehydrogenase
Pyruvate is produced by the process of glycolysis in the cytoplasm of a cell. From cytoplasm, it enters the mitochondrial matrix, where pyruvate dehydrogenase catalyses a set of reactions, in the presence of coenzymes, to covert pyruvate into acetyl coA. Acetyl coA then enters the Kreb's cycle or the Tricarboxylic acid (TCA) cycle.

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