Question

Which of the following is used in the conversion by pyruvate to acetyl CoA?

• A. Oxidative dehydrogenation
• B. Oxidative dehydration
• C. Oxidative phosphorylation
• D. Oxidative decarboxylation

Answer 1

The correct option is D Oxidative decarboxylation

Pyruvate decarboxylation or oxidative decarboxylation reaction is a biochemical reaction that uses pyruvate to form acetyl-CoA, releasing NADH, a reducing equivalent, and carbon dioxide via decarboxylation. This reaction is common in most organisms as a link between glycolysis and the citric acid cycle. So, the process used in conversion of pyruvate to acetyl CoA is oxidative decarboxylation.