P 5 0 is the partial pressure of oxygen at which haemoglobin is 50 - saturated- What will happen to the P 5 0 value if there is an increase in the partial pressure of Carbon dioxide and what effect will it have on the oxygen affinity of haemoglobin Hb-A- P 5 0 value will decrease and the oxygen affinity of Hb will decreaseB- P 5 0 value will increase and the oxygen affinity of Hb will increaseC- P 5 0 value will decrease and the oxygen affinity of Hb will increaseD- P 5 0 value will increase and the oxygen affinity of Hb will decrease

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Oxygen Dissociation Curve

P 5 0 is the ...

Question

$P_{5} 0$ is the partial pressure of oxygen at which haemoglobin is 50% saturated. What will happen to the $P_{5} 0$ value if there is an increase in the partial pressure of Carbon dioxide and what effect will it have on the oxygen affinity of haemoglobin (Hb)?

$P_{5} 0$ value will decrease and the oxygen affinity of Hb will increase

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$P_{5} 0$ value will increase and the oxygen affinity of Hb will increase

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$P_{5} 0$ value will decrease and the oxygen affinity of Hb will decrease

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$P_{5} 0$ value will increase and the oxygen affinity of Hb will decrease

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Solution

The correct option is D
$P_{5} 0$ value will increase and the oxygen affinity of Hb will decrease

When the partial pressure of carbon dioxide increases, the oxygen Hb dissociation curve shifts towards the right resulting in the increase of $P_{5} 0$ value. Consequently, the oxygen affinity of Hb decreases because more Hb binds with carbon dioxide.

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Similar questions

$P_{5} 0$ is the partial pressure of oxygen at which haemoglobin is 50% saturated. What will happen to the $P_{5} 0$ value if there is an increase in the partial pressure of Carbon dioxide and what effect will it have on the oxygen affinity of haemoglobin (Hb)?

Q. When under certain conditions,

P_{50}

value in blood rises, the affinity of respiratory pigment of combining with

O_{2}

will:

Q. Assertion :A rise in PC

O_{2}

, H+ ions and temperature shifts the Hb

O_{2}

dissociation curve to right. Reason: A rise in PC

O_{2}

or fall in pH decreases oxygen affinity for haemoglobin.

Q. Assertion :Oxyhaemoglobin dissociates near the organ tissue due to Bohr effect and oxygen is released. Reason: Increased CO

_{2}

concentration reduces the affinity of haemoglobin for oxygen.

Regarding assertion and reason, choose the correct option.

Assertion [A]: The affinity of hemoglobin for oxygen is dependent on the partial pressure of oxygen.

Reason [R]: Hemoglobin has a low affinity for oxygen.

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P50 is the partial pressure of oxygen at which haemoglobin is 50% saturated. What will happen to theP50 value if there is an increase in the partial pressure of Carbon dioxide and what effect will it have on the oxygen affinity of haemoglobin (Hb)?

$P_{5} 0$ is the partial pressure of oxygen at which haemoglobin is 50% saturated. What will happen to the $P_{5} 0$ value if there is an increase in the partial pressure of Carbon dioxide and what effect will it have on the oxygen affinity of haemoglobin (Hb)?