The correct option is
B Plasmid
pBR322 is a plasmid and was one of the first widely used
E. coli cloning vectors. The p stands for plasmid, and BR for Bolivar and Rodriguez (the Mexican postdoctoral researchers who constructed it). The plasmid pBR322 vector carries the genes for tetracycline and ampicillin resistance.
Therefore, the correct answer is option B.