Question

Plasma cells are derived from

• A. Cytotoxic T - cells
• B. Helper T - cells
• C. Memory B - cells
• D. Memory T - cells

Answer 1

The correct option is C Memory B - cells

Upon stimulation by a T cell, which usually occurs in germinal centers of secondary lymphoid organs like the spleen and lymph nodes, the activated B cell begins to differentiate into more specialized cells. Germinal center B cells may differentiate into memory B cells or plasma cells. The mechanism by which a B cell becomes one or the other of these is a process known as affinity maturation. Most of these B cells will become plasmablasts (or immature plasma cells), and eventually plasma cells, and begin producing large volumes of antibodies.

So, the correct answer is 'Memory B - cells'