Question

Pollutants, toxins and carcinogens are detoxified by

• A. $P_{450}$ and $P_{448}$
• B. S.E.R. in liver
• C. R.E.R. in liver
• D. Both A and B

Answer 1

The correct option is D Both A and B

• The smooth endoplasmic reticulum contains enzymes which catalyze a series of reactions that detoxifies lipid-soluble drugs, toxins and other harmful metabolic substances produced.
• Cytochrome (proteins with heme as a cofactor) P450 and P448 contains enzymes which help in the removal of carcinogenic compounds from the body.
• So, the correct answer is 'Both A and B'.