Question

Polymerisation of DNA nucleotides during the synthesis of lagging strand occurs in

• A. 3' $\to$ 5' direction
• B. 5' $\to$ 3' direction
• C. Any direction
• D. Promotor to terminator direction

Answer 1

Answer: (B)

5' $\to$ 3' direction

DNA replication is the process which the DNA is replicated and two copies are synthesized. The two strands of the DNA helix separate and the new strands are formed on the original strands, known as the template strands. The strand which is synthesized in 3'-5' direction is the leading strand and the strand which is synthesized in the opposite 5'-3' direction is the lagging strand which contains the Okazaki fragments.

Thus, the correct answer is option B.