Potential difference across resting membrane in neurons is negatively charged. This is due to differential distribution of the following ions:
A
Na+ and K+ ions
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B
Mg2+and Cl– ions
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C
Ca2+ and Mg2+ ions
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D
Ca2+ and Cl– ions
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Solution
The correct option is ANa+ and K+ ions Potential difference across resting membrane in neurons is maintained by sodium and potassium ions. The ion channels on the neural membrane control the movement of Na+ and K+ ions on both inner and outer side of nerve cell.
Calcium and magnesium ions are not related with nerve excitation rather are involved in other biological functions. Ca2+ ions are related to muscle metabolism where as Mg2+ ions act as a cofactor. Cl– ions are one of the most important electrolytes in blood.