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Question

Protons (as NADH, FADH2) taking part in oxidative phosphorylation enter mitochondria as

A
Glucose
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B
Oxaloacetic acid
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C
Acetyl CoA
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D
Pyruvate
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Solution

The correct option is B Pyruvate
The pyruvic acid generated in the glycolysis enters into the mitochondrial matrix and undergoes oxidative decarboxylation to produce acetyl coenzyme A. Acetyl coenzyme A further enters into 8 cyclic step process called Kreb's cycle. During these processes, NADH and FADH2 are produced which finally reduce oxygen to water. The respiratory breakdown of glucose in the presence of oxygen is an oxidative process. during this process release of protons occurs which are picked by NAD and FAD AND and they get reduced. Thus, it is pyruvate which first enters the mitochondria for oxidative phosphorylation to happen.
Thus, the correct answer is option D.

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