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Question

RO||CZ+NuRO||CNu+Z
The rate of the reaction is the fastest when Z is:

A
Cl
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B
NH2
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C
OC2H5
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D
OCOCH3
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Solution

The correct option is A Cl
Acid halids are the most reactive towards nucleophilic substitutions.
The actual order is as follows:
Acid halides > Acid anhydride > Ester > Amide.

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