R−O||C−Z+Nu−⟶R−O||C−Nu+Z− The rate of the reaction is the fastest when ′Z′ is:
A
Cl
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B
NH2
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C
OC2H5
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D
OCOCH3
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Solution
The correct option is ACl Acid halids are the most reactive towards nucleophilic substitutions. The actual order is as follows: Acid halides > Acid anhydride > Ester > Amide.