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Question

Ramesh has undergone organ transplantation. In order to avoid failure of the transplant or organ rejection, which of the following can be prescribed to him?

A
Cyclosporin A
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B
Statins
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C
Streptokinase
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D
Lipase
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Solution

The correct option is A Cyclosporin A
Organ donation is the process of removing an organ from a live or dead individual surgically and placing it in another individual. The common organs that are transplanted are the heart, kidneys, liver or skin.
This procedure elicits an immune response in the body of the patient receiving the organ as it is a foreign tissue for the body and as a result immune cells start to attack it.
In order to prevent this, the immune system has to be surpressed such that it does not destroy the transplanted organ. Cyclosporin A, a chemical produced by the fungus Trichoderma polysporum, has the capability of suppressing the immune system by inhibiting the activation of T-cells.

Statins are produced by Monascus purpureus, a yeast. It helps in lowering blood cholesterol levels by inhibiting the enzyme involved in cholesterol synthesis in the body.

Streptococcus bacteria produces an enzyme called streptokinase which is genetically modified and used to remove clots from blood vessels of patients who have suffered from a heart attack.

Lipases are enzymes produced by some species of bacteria and fungi and are used in detergents for the removal of oily stains from laundry.

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