Question

Read the following statements and choose the correct option.
1. RNA polymerase associates transiently with ‘Rho’ factor to initiate transcription.
2. In bacteria transcription and translation takes place in the same compartment.
3. RNA polymerase I is responsible for transcription of tRNA.
4. When hnRNA undergoes capping process, adenylate residues are added at 3’ end in a template independent manner.
5. hnRNA is precursor of mRNA

Answer 1

Statement 2

• Bacteria are prokaryotes and do not have a well defined nucleus. In bacteria, the translation begins even before the transcription is complete.
• Both transcription and translation are coupled and they take place in the same compartment, i.e, the cytoplasm.
• Thus, statement 2 is correct.

Statement 5

• In eukaryotes, the primary RNA transcript is known as heterogeneous RNA or hnRNA.
• It undergoes chemical modifications in the nucleus to form functional mRNA before being transported out into the cytoplasm for translation.
• Hence hnRNA is rightly said to be the precursor to mRNA.
• Thus, statement 5 is correct.

Final answer:

(a) 2 and 5 only are correct