Question

Read the following statements carefully and select the correct option.
Statement I: Insulin is produced by alpha cells of islets of Langerhans.
Statement II: During maturation of insulin from proinsulin, C peptide is removed for proper folding.

• A. Both I and II are true
• B. I is true but II is false
• C. I is false but II is true
• D. Both I and II are false

Answer 1

The correct option is C I is false but II is true

Insulin is a peptide hormone which is produced by beta cells of islets of Langerhans. These cells are present in the endocrine portion of pancreas. When the sugar level rises in blood, the insulin hormone is secreted by pancreas causing the uptake of glucose into the cells.

Proinsulin is a single polypeptide chain composed of the A and B subunits of insulin joined by the C peptide region. This C peptide is not present in the mature insulin and is removed during the maturation process.