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Question

Read the following statements.

I. Cancerous cells are fast-dividing cells that display contact inhibition
II. Metastasis is the most dreaded problem of any cancer
III. Tumours are always confined to their original location

Which of the above statements are true?


A
I and II
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B
I and III
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C
Only II
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D
I, II and III
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Solution

The correct option is C Only II

Cancer is one of the most dreaded diseases of human beings and a major cause of death all over the world.

There are several agents (physical, biological and chemical) that cause the transformation of the normal cells into cancerous cells.

The cancerous cells differ in several ways from the normal cells.

The cell growth and differentiation are highly controlled and regulated in the normal cells. However, in the cancer cells, these regulatory mechanisms are lost and therefore these cells divide uncontrollably giving rise to masses of cells called tumors.

In the normal cells, the cell growth stops when two or more cells come in contact with each other. This property of normal cells is called contact inhibition due to which the uncontrolled growth of cells is inhibited.

Unfortunately, the property of contact inhibition is lost in cancer cells and they divide in an uncontrolled manner forming a mass of cells called tumors.

A tumour is classified into following types based on its ability to undergo metastasis (spreading to other locations):

  • Benign tumor - These tumours are localized at a particular location in the body and do not spread to the other parts of the body. Such tumors are generally harmless.
  • Malignant tumor - These tumours are cancerous – they will grow quickly and spread to other normal tissues of the body. This ability to spread is called metastasis. Usually, cancer cells metastasize when they get into the bloodstream or the lymph nodes and form secondary tumours across various sites in the body.
Hence, only statement II is true.

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