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B
More CO2 concentration in blood
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C
Accumulation of blood in brain
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D
All of the above
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Solution
The correct option is B More CO2 concentration in blood During breathing process, the level of CO2 in blood acts on the medulla oblongata which controls the respiratory mechanism. High levels of carbon dioxide correspond with high levels of acid (low pH) and signal the need for more oxygen. A rise in PCO2 (a condition called as hypercapnia) decreases the pH level of cerebrospinal fluid. This excites the central chemoreceptors resulting in an increase in the depth and rate of respiration, a condition called hyperventilation. The resulting increase in alveolar ventilation flushes carbon dioxide out of the blood which increases the blood pH.