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Question

Saline drip is given to a Cholera patient because

A
NACI kills Vibrio cholera
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B
NACI generates ATP
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C
Na+ ions stops nerve impulse and hence sensation of pain
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D
Na+ ions help in retention of water in body tissue
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Solution

The correct option is D Na+ ions help in retention of water in body tissue

Patients suffering from cholera are given a saline drip because Na+ ions help in the retention of water in the body tissues. Severe diarrhea, vomiting, watery stools are the chief symptoms of cholera. All these lead to dehydration. Actually, cholera toxin secreted by Vibrio cholerae causes, through a series of metabolic reactions, the continuous activation of adenylate cyclase of intestinal epithelial cells. The resultant high concentration of c-AMP triggers continuous secretion of chlorine, bicarbonate, and water into the lumen of the intestine. Administration of saline not only supports the sodium-potassium pump through which water in the cell is restored, but glucose is also imported along with sodium. Thus, the correct answer is option D.


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