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Question

Select the appropriate words to fill in the blanks.

  1. A primordial follicle becomes primary follicle when _____(i)____  become enlarged, many layered and cuboidal.
  2. The ovum is separated from the granulosa cells by ___(ii)_____.
  3.  The theca interna minorly, and the granulosa cells majorly, begin to secrete a fluid rich in estrogen. At this stage  ______(iii)_____ follicle is formed.
  4.  The formation of the antral cavity marks the formation of ___(iv)_______ follicle.

  1. i  theca interna            ii  granulosa cells         iii  secondary        iv  tertiary

  2. i  zona pellucida           ii  theca interna          iii  secondary         iv  tertiary

  3. i  granulosa cells         ii  zona pellucida        iii  secondary        iv   tertiary

  4. i  zona pellucida         ii  theca interna          iii  tertiary              iv  secondary  


Solution

The correct option is C

i  granulosa cells         ii  zona pellucida        iii  secondary        iv   tertiary


During the developmental stages of the ovarian follicles when the primordial follicle gets surrounded by a few more layers of granulosa cells, it forms the primary follicle. These primary follicles grow in size under the influence of FSH and LH. Spindle shaped cells from the ovarian interstitium accumulate around the granulosa cells to form another layer of cells called the theca. The formation of the secondary follicle is marked by this thecal layer getting differentiated into inner theca interna and outer theca externa. Upon further development, cells of theca interna and the granulosa cells secrete estrogen-rich fluid which starts accumulating internal to the theca interna leading to the formation of the antral cavity. The formation of the antral cavity marks the formation of the tertiary follicle.

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