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Question

Select the favourable conditions required for the formation of oxyhaemoglobin at the alveoli.

A
Low p02, low pCO2, more H+, higher temperature
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B
High p02, low pCO2, less H+, lower temperature
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C
Low p02, high pCO2, more H+, higher temperature
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D
High pO2, high pCO2, less H+, higher temperature
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Solution

The correct option is B High p02, low pCO2, less H+, lower temperature
RBC contains haemoglobin, an iron containing pigment. It helps in the transport of respiratory gases (oxygen and carbon dioxide).

Each molecule of haemoglobin is made up of four haeme groups surrounding a globin group.

Oxygen and carbon dioxide bind to haemoglobin in a reversible manner forming oxyhaemoglobin and carbamino-haemoglobin respectively.

There are several conditions that affect the formation and dissociation of oxyhaemoglobin. These include:

1. Partial pressure of oxygen and carbon dioxide.
2. Hydrogen ion concentration
3. Temperature

In the alveoli of lungs, there is high pO2, low pCO2, lesser H+ concentration and lower temperature. All these factors are favourable for the formation of oxyhaemoglobin at the alveoli.

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