Question

Shivering in malaria is due to

• A. Toxin released during the merozoite release from the lysed RBC
• B. Signet ring
• C. Both A and B
• D. None of the above

Answer 1

Answer: (A)

Toxin released during the merozoite release from the lysed RBC

Each merozoite can infect a red blood cell. Within the RBCs, the merozoite matures either into a uninucleated gametocyte, the sexual stage, infectious for Anopheles mosquitoes. The fever and the shivering are associated with the rupture of erythrocytic-stage schizonts. In severe malaria, parasitized RBCs may obstruct capillaries and postcapillary venules, leading to local hypoxia and the release of toxic cellular products.
So, the correct answer is option A.